Three-color Fiber Photometry and Integrated Optogenetic Stimulation Systems
TDT is the long-time industry leader in fiber photometry.
Our turn-key optical solutions have been used by researchers to pioneer the field of fiber photometry. Our lock-in amplifier systems are proven to be the most sensitive and versatile systems on the market.
TDT’s latest innovations simplify setup greatly with our integrated iX7 photometry module.
Lock-in Amplification is Best
TDT systems us lock-in amplification to pick up light changes with the sensitivity of just a few photons.
Our system allows excitation lights to run simultaneously, so there is no post-processing for signals.
Record green and red fluorescence in the same site with the best signal-to-noise possible.
Our systems provide easy integration of optogentic stimulation to either the same site as photometry recordings or separate optical implants.
Synapse and TDT hardware easily integrates your optogenetic stimulation with synchronized photometry, behavior, video tracking, and electrophysiological signals. This means you can do closed-loop opto stim in real-time with no jitter, lag, or issues.
Animal artwork (modified or otherwise) from BioRender
Why TDT?
When you choose a TDT behavioral neuroscience recording system you choose legacy, innovation, and commitment. Every system is designed and assembled at our headquarters in Alachua, Florida by our long-time employees.
Tucker-Davis has been the industry leader in turn-key fiber photometry solutions from the beginning of the techniques' adoption. Early use of our RX8 and RZ5P equipment showed that TDT equipment was perfect for lock-in amplification and collection of the low light signals produced in GCaMP cell fluorescence DOI 10.1073] (methods here [Calipari et al. 10.1073/pnas.1521238113]). We have kept pushing novel recording innovations and are still producing new top systems to this day, such as the RZ10x, iX6, and iX7.
The journey of our photometry equipment began with coordinative control of external equipment to perform simultaneous LED stimulation and photosensor recording. However, we realized that complete integration of each component was necessary to exceed the expectations of our customers and to deliver the best product possible. This meant that we needed to build our own LED drivers, photosensors, and optical filter design. The RZ10x was our first fully-integrated fiber photometry system and has been used with resounding success so far in many fields]. This same spirit of design and innovation has been pushed further into our iCon platform, yielding the creation of our iX6 (an RZ10x-like iCon module) and iX7 (a photometry module with LEDs and photosensors fully integrated with in-line optical filtering).
A full-time Technical Support staff is a part of your system for free and for life. You call us and we pick up. We are experts with advanced degrees in neuroscience and neural engineering and take great pride in making sure you get the best experience possible out of using our top-tier recording system. We challenge you to find a researcher who has worked with our Support team who would not recommend us first.
