Fiber Photometry
RECORD REAL-TIME FLUOROPHORE RESPONSES WITH THE RZ10X
Description
Specs & Resources
Publications
Fiber photometry is a calcium imaging method for detecting neural activity. Researchers can use genetic animal models and fluorescent proteins, such as calcium (GCaMP) and dopamine (dLight), to study specific brain circuits.
TDT’s Fiber Photometry is an out-of-the-box solution designed for researchers. Our user-friendly Our user-friendly Synapse software provides a seamless interface to the real-time LUX RZ10X processor. Integrated LUX LEDs and photosensors streamline hardware setup and debugging. TDT allows you to focus on the research and not the equipment.
Synapse and our LUX hardware simplify fiber photometry. With Synapse, record and view your fluorophore responses in real-time, while behavior and video data is automatically time-locked. Optogenetics and electrophysiology can also be incorporated for multi-modal and closed-loop experiments.
Matlab SDK and Python SDK
Guo … Polley, et al “The Cholinergic Basal Forebrain Links Auditory Stimuli with Delayed Reinforcement to Support Learning”. Neuron Jul, 2019. doi: 10.1016/j.neuron.2019.06.024
Parker … Bruchas, et al “A Paranigral VTA Nociceptin Circuit that Constrains Motivation for Reward”. Cell Jul, 2019. doi: 10.1016/j.cell.2019.06.034
Choi … McNally, et al “Paraventricular Thalamus Controls Behavior during Motivational Conflict”. The Journal of Neuroscience Jun, 2019. doi: 10.1523/jneurosci.2480-18.2019
Feng … Li, et al “A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine”. Neuron May, 2019. doi: 10.1016/j.neuron.2019.02.037
Cameron … Witten, et al “Increased Cocaine Motivation Is Associated with Degraded Spatial and Temporal Representations in IL-NAc Neurons”. Neuron May, 2019. doi: 10.1016/j.neuron.2019.04.015
Bai … Knight, et al “Genetic Identification of Vagal Sensory Neurons That Control Feeding.”. Cell , 2019. doi: 10.1016/j.cell.2019.10.031
Robinson … Gradinaru, et al “Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1”. eLife , 2019. doi: 10.7554/elife.48983
Pascoli … Lüscher, et al “Stochastic synaptic plasticity underlying compulsion in a model of addiction”. Nature Dec, 2018. doi: 10.1038/s41586-018-0789-4
Reed … Britt, et al “Coordinated Reductions in Excitatory Input to the Nucleus Accumbens Underlie Food Consumption”. Neuron Sep, 2018. doi: 10.1016/j.neuron.2018.07.051
Walsh … Malenka, et al “5-HT release in nucleus accumbens rescues social deficits in mouse autism model”. Nature Aug, 2018. doi: 10.1038/s41586-018-0416-4
Saunders … Janak, et al “Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties”. Nature Neuroscience Jul, 2018. doi: 10.1038/s41593-018-0191-4
