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Recorded TDT Talks

Sleep Studies

Dr. Min Xu

Basal forebrain control of sleep-wake cycle: from neural circuits to sleep homeostasis

Completed

Recorded Talk

 

Jimmy Dooley, PhD and Mark Blumberg, PhD

Myoclonic twitches during REM sleep drive neural activity in motor thalamus and motor cortex in preweanling rats

Completed

Recorded Talk

 

Hanna Haya, PhD and Yuval Nir, PhD

What makes us unresponsive when we sleep? A role for reduced locus coeruleus-noradrenaline activity

Completed

Recorded Talk

 


Fiber Photometry

Ted Hsu, PhD

Utilization of in vivo fiber photometry to examine the control of need-driven goal-directed behaviors

Recorded Webinar

To understand how need states (e.g. hunger, thirst) mediates goal-directed behaviors, we expressed protein-based fluorescent sensors in rats to measure, with in vivo fiber photometry, ventral tegmental area (VTA) dopamine neuron activity (Cre-dependent gCaMP in TH-Cre+ rats) or dopamine release (dLight1.2) in the nucleus accumbens shell (NAc shell). We then combined this approach with behavior, chemogenetics, pharmacology, and extensive analyses to elucidate the relationship between the mechanisms that regulate need-states and the mesolimbic dopamine system that subsequently allows for the expression of appropriate goal-directed behaviors.

 

Philip Jean-Richard-dit-Bressel, PhD and Gavan McNally, PhD

Mesolimbic dopamine activity signatures of relapse

Recorded Webinar

We will discuss the use of photometry to map the mesolimbic dopamine signatures of relapse to drug seeking, including the use of representational similarity analysis to overcome the problem of correspondency or mapping between different signals from different sensors and brain regions.

 

David Barker, PhD

Using a novel photometry modular analysis tool to examine pain responses in the hypothalamus

Recorded Webinar

The photometry modular analysis tool (pMAT) is a novel graphical user interface used for common types of data analysis in fiber photometry calcium imaging. We will unveil this suite in the present talk and exhibit some data recently collected using the tool which demonstrates a role for the preoptic area of the hypothalamus in pain processing.

 

Jennifer Rinker, PhD and Patrick Mulholland, PhD

Prefrontal cortical (PFC) activation and circuitry during ethanol intake

Recorded Webinar

Jennifer Rinker, PhD and Patrick Mulholland, PhD of MUSC present their work using fiber photometry to explore prefrontal cortical (PFC) activation and circuitry during ethanol intake.


Recorded Sales Webinars

 

TDT | Integrating Electrophysiology and fMRI

Recorded Webinar

 

TDT | Integrating Electrophysiology and fMRI

TDT’s recent advances in tools for concurrent electrophysiology recordings with fMRI are discussed.

Researchers Cherry (Jiayue) Cao (PhD student | PI: Dr. Zhongming Liu | University of Michigan) and Yuncong Ma (PhD student | PI: Dr. Nanyin Zhang | Penn State University) will also describe their hands-on experience with the TDT system.

 

 

 

TDT | Introduction to the RZ10x for Fiber Photometry

Recorded Webinar

 

TDT | Introduction to the RZ10x for Fiber Photometry

Learn how you can streamline your optogenetic and calcium imaging experiments for studying neural circuits.

The RZ10X and integrated LUX components are discussed as well as the updated Synapse software features. See how the flexibility for smoother fiber photometry experiments.

 


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