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Optical Neuroscience

TDT’s LUX processors offer neuroscientists products

for calcium imaging and optogenetics

What is LUX?

Calcium imaging and optogenetics have revolutionized how neuroscientists understand neural circuitry. Standard electrophysiology records from 10s to a few 100s of neurons with no specificity. With calcium imaging, you can record from 100s to 1000s of neurons, targeting a structure or functional pathway. With optogenetic stimulation, you can target specific neurons and structures without the potential devasting damage that electrical stimulation generates.

TDT’s LUX devices are the next generation of research tools for calcium-imaging and optogenetics. The first LUX processor builds on the previous fiber photometry processor (RZ5P) by integrating LED drivers, LED sources and photoreceivers. This integrated system allows for easier fiber photometry setup and more flexible customization. TDT has also incorporated miniaturized fluorescence microscopy into the latest LUX processor.

Why TDT?

TDT’s engineering knowledge of real-time signal processing and 20+ years of electrophysiology expertise are the backbone for a new era in calcium-based and optogenetic neuroscience. TDT developed the first fiber photometry system that uses lock-in amplification for simultaneous multi-color signal detection. With this feature, researchers can easily view, acquire, and analyze GCaMP and other fiber photometry responses in real-time. The LUX processors seamlessly incorporate calcium imaging and optogenetic stimulation with behavioral monitoring and classic electrophysiology. TDT’s focus on expandability and integration allows researchers to collect all their neuroscience data in one place. TDT also emphasizes user friendly interfaces and strong support to help researchers get experiments up and running faster.