Welcome to TDT Knowledge Hub
This site is the home for all TDT hardware and software documentation, guides for specific applications, and tech notes for troubleshooting.
System 3 Hardware
System 3 Installation GuideUnpacking, connecting and testing your System 3 hardwareUpdated 2026/10/07
zBusMon Test UtilityTest hardware communicationUpdated 2026/09/22
Hardware ManualsManual and tech specs for all TDT System 3 HardwareUpdated 2026/10/07
RPvdsEx ManualGraphical programming environment for System 3 real-time processorsUpdated 2026/10/07
ActiveX User ReferenceControl System 3 hardware from MATLAB, Python or C++ with the RPcoX, PA5x and ZBUSx controlsUpdated 2026/10/07
Direct Hardware Access ToolsControl hardware from MATLAB or Python with the TDTRP, TDTPA5 and TDTZBUS ActiveX wrappersUpdated 2026/09/03
I/O DelaysSample delay considerations for TDT hardware I/O in Synapse, RPvdsEx and OpenExUpdated 2026/10/07
Corpus Hardware EmulatorEmulate hardware for remote experiment designUpdated 2026/09/03
Synapse Software
SynapseMulti-channel acquisition and stim presentation softwareUpdated 2026/10/07
PynapsePython integration inside SynapseUpdated 2026/10/07
Synapse APIControl Synapse from custom applications outside SynapseUpdated 2026/10/05
Lab Rat User GuideGetting Started with Lab Rat and SynapseLiteUpdated 2026/10/07
BioSig Software
BioSigRZABR & DPOAE recording and analysis software for RZ6Updated 2026/09/21
SigGenRZStimulus Signal Design Application for BioSigRZUpdated 2026/09/03
SigCalRP User GuideSpeaker calibration and SigGenRP normalization filesUpdated 2026/09/03
Data Tools
Offline Data Analysis ToolsTools for reading Synapse data into Python & MATLABUpdated 2026/10/07
Online Control and Data Analysis ToolsTools for reading live Synapse dataUpdated 2026/09/03
OpenScope User GuideData Replayer and Online Viewer for SynapseUpdated 2026/09/03
OpenBrowser User GuideData Export from Tanks to ASCII, NEX, PLX, DDT, and EDFUpdated 2026/10/07
OpenExplorer User GuideInteractive Visualization and Analysis of Tank DataUpdated 2026/09/03
OpenSorter User GuideOffline Spike Sorting for Tank DataUpdated 2026/09/03
Application Guides
ABR User GuideABR Measurements with RZ6 and Medusa4ZUpdated 2026/10/07
DPOAE User GuideDPOAE Measurements with RZ6Updated 2026/10/07
Fiber Photometry User GuideFiber Photometry Guide using the RZ10x processorUpdated 2026/10/07
EEG and EMG with iA4Low impedance EEG and EMG recording with the iA4 differential bioampUpdated 2026/10/01
fMRI User GuideEphys Recording in fMRI using TDTUpdated 2026/10/07
Electrical Stimulation User GuideElectrical Stimulation with Subject Interface (SI)Updated 2026/10/07
Understanding Digital I/OTTL pulses, digital words, and connecting TDT to third-party devicesUpdated 2026/10/07
Channel Mapping GuideMap vendor probe and adapter pinouts to TDT headstages in SynapseUpdated 2026/10/07
Support
Tech NotesKnown issues & anomalies with TDT hardware & softwareUpdated 2026/10/07
Lightning VideosShort video tips and tricks when using your TDT systemUpdated 2026/08/03
Other PDF Manuals
Legacy Software
Documentation for superseded software, kept for users maintaining existing installations.