New Frontiers in Neuroscience

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IZ2M & IZ2MH Stimulator

A High-Channel Count Macro Stimulator

Easily configure your research setup with the IZ2M’s, compact and rack-mountable form factor. Ensure continuous, clean electrical power supply with biomedical grade electrical isolation.  Choose between standard, micro stimulation with the IZ2M or high current, macro stimulation with the IZ2MH.


Signals acquired on TDT’s RZ platform can be used to trigger the IZ2 Stimulator in less than a millisecond. Harness the power to control up to 128 channels (standard) or 64 channels in high current mode. High quality converters provide over 80 dB of dynamic range from 30 nAmps to 300 microamps.

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Research Applications

  • Deep brain stimulation
  • Seizure disruption
  • Spike triggered stimulation

RZ2 BioAmp Processor

Real-time processing and programmable control of PZ5 modes and digital filtering.

Passive ZIF-Clip® Headstages

Digitize at the headstage utilizing an integrated amplifier chip to yield a low noise electrode recording interface.

ACO32 Commutator

A motorized commutator with built-in support for both neural recording and optogenetic stimulation.

IZ2 Stimulation Gizmos

Supported by Synapse for Easy Visual Configuration

The IZ2M Stimulator is used with the RZ Bioamp Processor as part of a programmable microstimulator system that delivers user-defined stimuli through multichannel electrodes.


SpikePac is a powerful extension Gizmo for TDT’s Synapse software suite designed specifically for researchers doing multi-channel neural recordings.  TDT recently added IZ2StimGen, a stimulation interface to our SpikePac software.


The all new IZ2StimGen macro implements configuration and control of the IZ2M Stimulator.  It supports monophasic or biphasic pulse train stimulation with up to four stimulus configurations.  It features an easy to use interface for stimulus design, impedance checking, and real-time stimulus presentation through the IZ2M Control in Synapse.

See all the Synapse Gizmos >

RZ2 BioAmp Processor >


More Capabilities of the IZ2M Stimulator's

The IZ2H and IZ2MH is a high current range version of the IZ2 and is available up to 64 stimulus channels and is rack mountable.


  • Delivers a maximum of 3 mAmps(300 μAmps for the IZ2M) of current per electrode up to 12 V on up to ten electrodes simultaneously.
  • The stimulator’s power supply has been validated to ensure 4,000 volts of isolation between the input and output, 1,500 volts of isolation between the input and ground, and 500 volts of isolation between the output and ground.
  • Full medical grade isolation between the mains power and the electrode outputs ensures electrical isolation, and additional safety features ensure safe operation at all times

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